| Anmol Chemicals is the pioneer manufacturers of Calcium Dobesilate, Pharmaceutical Excipients Food & Flavor chemicals in India. We supply Halal and Kosher Calcium Dobesilate made in an ISO9001, ISO22000 (FSSC22000) cGMP and GLP certified facility. Our group has several manufacturing facilities spread across the world, supported by toll manufacturers and representatives in UAE, Europe, Africa, USA, China and has several associated manufacturing facilities spread across India. All the Information on Uses and Technology on Manufacture of Calcium Dobesilate is in these pages. |
| The units have one or more of the certifications like FDA GMP, ISO 9001, ISO 22000, HACCP, REACH, Kosher & Halal |
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Calcium Dobesilate BP Ph Eur Grade Manufacturers
Calcium Dobesilate SDS MSDS Sheet of Manufacturers
Calcium Dobesilate Monohydrate BP
Ph. Eur.
C12H10CaO10S2,H2O --- 436.4 --- 20123-80-2
DEFINITION
Calcium di(2,5-dihydroxybenzenesulfonate) monohydrate.
Content: 99.0 per cent to 101.0 per cent (anhydrous substance).
CHARACTERS
Appearance: White or almost white, hygroscopic powder.
Solubility: Very soluble in water, freely soluble in anhydrous ethanol, very slightly soluble in 2-propanol, practically insoluble in methylene chloride.
IDENTIFICATION
A. Ultraviolet and visible absorption spectrophotometry.
B. Mix 1 mL of ferric chloride solution, 1 mL of a freshly prepared 10 g/L solution of potassium ferricyanide and 0.1 mL of nitric acid R. To this mixture add 5 mL of freshly prepared solution S (see Tests): a blue colour and a precipitate are immediately produced.
C. 2 mL of freshly prepared solution S gives reaction of calcium.
TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water and dilute to 100 mL with the same solvent.
Appearance of solution: Solution S, when freshly prepared, is clear and colourless.
pH: 4.5 to 6.0 for solution S.
Related substances: To pass the test of Liquid chromatography
Iron: Maximum 10 ppm, determined on 10 mL of solution S.
Water: 4.0 per cent to 6.0 per cent, determined on 0.500 g.
ASSAY
Dissolve 0.200 g in a mixture of 10 mL of water R and 40 mL of dilute sulfuric acid R. Titrate with0.1 M cerium sulfate, determining the end-point potentiometrically. 1 mL of 0.1 M cerium sulfate is equivalent to 10.45 mg of C12H10CaO10S2.
STORAGE
In an airtight container, protected from light.
IMPURITIES
Specified impurities A: benzene-1,4-diol (hydroquinone).
Manufacturers
Anmol Chemicals
S-8, SARIFA MANSION, 2ND FLANK ROAD, CHINCHBUNDER, MUMBAI 400009, INDIA
TEL: (OFFICE) 91-22-23770100, 23726950, 23774610, 23723564. FAX: 91-22-23728264
e-mail: anmolc@mtnl.net.in
Exports to USA, Canada, UAE, Dubai, South Africa, Tanzania, Kenya, Nigeria, Egypt, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Europe Netherlands, Italy, Spain, Germany, Portugal, France, Malaysia, Indonesia, Thailand, Korea, Japan, etc.
Copyright and Usual Disclaimer is Applicable. 13 January, 2022
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